2-Pyridineethanamine → 1,8,8-Trimethyl-3-[2-(2-pyridinyl)ethyl]-3-azabicyclo[3.2.1]octane-2,4-dione

HRID 867944

반응식

HRID 867944 반응식
[C:1]1(=[O:13])[O:10][C:8](=O)[CH:7]2[CH2:11][CH2:12][C:2]1([C:4]2([CH3:6])[CH3:5])[CH3:3].[NH2:14][CH2:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1>N1C=CC=CC=1>[CH3:3][C:2]12[C:4]([CH3:5])([CH3:6])[CH:7]([CH2:11][CH2:12]1)[C:8](=[O:10])[N:14]([CH2:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1)[C:1]2=[O:13]

참가 물질

4

반응물 2

HCID 759192-PyridineethanamineHCID 948341,8,8-Trimethyl-3-oxabicyclo[3.2.1]octane-2,4-dione

생성물 1

HCID 142350661,8,8-Trimethyl-3-[2-(2-pyridinyl)ethyl]-3-azabicyclo[3.2.1]octane-2,4-dione

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A mixture of (-) camphoric anhydride 5 g (0.029 mol), 2-(2-aminoethyl)pyridine 3.6 (0.03 mol) and 50 ml of pyridine was refluxed overnight. The solvent is removed under reduced pressure and the remaining oil boiled in 20 ml of ethanol and allowed to cool.

후처리

  1. temperaturewas refluxed overnight
  2. customThe solvent is removed under reduced pressure
  3. temperatureto cool

출처 및 근거

ORD 기록
ord-14d27eb0342e4f14801d1f2da1572273
출처 데이터셋
uspto-grants-1988_10
특허 번호
US04777254

연결된 노트

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