Benzoic acid, 4-ethyl-2-methyl-, methyl ester → 4-Ethyl-2-methylbenzoic acid

HRID 868739노트

반응식

HRID 868739 반응식
[CH2:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9]C)=[O:8])=[C:5]([CH3:13])[CH:4]=1)[CH3:2]>[OH-].[Na+]>[CH2:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([OH:9])=[O:8])=[C:5]([CH3:13])[CH:4]=1)[CH3:2]

참가 물질

3

반응물 1

HCID 10773666Benzoic acid, 4-ethyl-2-methyl-, methyl ester

생성물 1

HCID 105350174-Ethyl-2-methylbenzoic acid

시약·촉매·용매 1

HCID 14798Sodium Hydroxide용매

반응 조건

온도
60 °C

실험 절차

Methyl 4-ethyl-2-methylbenzoate (example 10c) (2.37 g) was dissolved in aq. NaOH (1M, 40 mL) and the solution heated at 60° C. overnight. The mixture was washed with hexanes and the aqueous layer was acidified with 6N HCl to pH 2. The title product was obtained as a white precipitate, following filtration and drying (2.17 g, 80%).

후처리

  1. washThe mixture was washed with hexanes

출처 및 근거

ORD 기록
ord-a615ba1b682243c6b46e338c458eba06
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08968708B2

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