Hydrochloric Acid → HCID 66642852, 화합물
반응식
[NH2:1][CH:2]1[CH2:7][CH2:6][C:5]([NH:9]C(=O)OC(C)(C)C)([CH3:8])[CH2:4][CH2:3]1.C(O)C.[ClH:20]>C(OCC)(=O)C>[ClH:20].[ClH:20].[CH3:8][C:5]1([NH2:9])[CH2:6][CH2:7][CH:2]([NH2:1])[CH2:3][CH2:4]1참가 물질
5
실험 절차
To a mixture of tert-butyl (4-amino-1-methylcyclohexyl)carbamate (Preparation Example 399) (3.73 g) and ethanol (30 mL), 4M hydrogen chloride in ethyl acetate (30 mL) was added under ice cooling and stirred at room temperature for 20 hours. The precipitated solid was collected by filtration and washed with ethyl acetate to give 1-methylcyclohexane-1,4-diamine dihydrochloride (2.10 g) as a white solid.
후처리
- additionwas added under ice cooling
- filtrationThe precipitated solid was collected by filtration
- washwashed with ethyl acetate
출처 및 근거
- ORD 기록
- ord-a3defbda903c4b33adc2cbe920d52327
- 출처 데이터셋
- uspto-grants-2015_03
- 특허 번호
- US08969336B2
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