Acetic Anhydride → HCID 86722248, 화합물

HRID 869403노트

반응식

HRID 869403 반응식
[Br:1][C:2]1[C:10]([OH:11])=[CH:9][CH:8]=[C:7]([OH:12])[C:3]=1[CH:4]=[N:5]O.[C:13]([O-:16])(=O)[CH3:14].[Na+].[CH3:18][C:19](OC(C)=O)=[O:20]>>[Br:1][C:2]1[C:3]([C:4]#[N:5])=[C:7]([O:12][C:19]([CH3:18])=[O:20])[CH:8]=[CH:9][C:10]=1[O:11][C:13]([CH3:14])=[O:16]

참가 물질

4

반응물 3

HCID 7918Acetic AnhydrideHCID 517045Sodium AcetateHCID 136348391HCID 136348391, 화합물

생성물 1

HCID 86722248HCID 86722248, 화합물수율 69.1%

실험 절차

A mixture of 12B (45 g, 0.193 mol) and sodium acetate (3 g) in Ac2O (200 mL) was heated to reflux overnight. The reaction mixture was evaporated under reduced pressure to remove Ac2O. The residue was poured into water and stirred for 1 hour. The precipitated solids were collected by filtration and dried to give 12C (40 g, 69.1% yield).

후처리

  1. temperaturewas heated
  2. temperatureto reflux overnight
  3. customThe reaction mixture was evaporated under reduced pressure
  4. customto remove Ac2O
  5. additionThe residue was poured into water
  6. filtrationThe precipitated solids were collected by filtration
  7. customdried

출처 및 근거

ORD 기록
ord-4690db8eb6fb4922a5ce28c8b3ae7e17
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08969373B2

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