Bromide ion → Tert-butyl 2-[3-acetyl-4-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-1,3-oxazolidin-5-yl]-4-hydroxy-4-phenylpyrrolidine-1-carboxylate

반응식

[Br-:1].[C:9]([CH3:10])([CH3:11])([CH3:12])[O:13][C:14](=[O:15])[N:16]1[CH:17]([CH:22]2[CH:23]([CH2:32][c:33]3[cH:34][c:35]([F:40])[cH:36][c:37]([F:39])[cH:38]3)[N:24]([C:29]([CH3:30])=[O:31])[C:25]([CH3:27])([CH3:28])[O:26]2)[CH2:18][C:19](=[O:21])[CH2:20]1.[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[c:2]1([Mg+:8])[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[c:2]1([C:19]2([OH:21])[CH2:18][CH:17]([CH:22]3[CH:23]([CH2:32][c:33]4[cH:34][c:35]([F:40])[cH:36][c:37]([F:39])[cH:38]4)[N:24]([C:29]([CH3:30])=[O:31])[C:25]([CH3:27])([CH3:28])[O:26]3)[N:16]([C:14]([O:13][C:9]([CH3:10])([CH3:11])[CH3:12])=[O:15])[CH2:20]2)[cH:3][cH:4][cH:5][cH:6][cH:7]1