Hydrochloric Acid → Octanoate

HRID 871800

반응식

HRID 871800 반응식
[C:1]([O-:10])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[Na+].[CH3:12][C@@H:13]1[N:34]2[C:17]3[C:18]([C:30]([C:32]([C:35]([OH:37])=[O:36])=[CH:33]2)=[O:31])=[CH:19][C:20]([F:29])=[C:21]([N:22]2[CH2:27][CH2:26][N:25]([CH3:28])[CH2:24][CH2:23]2)[C:16]=3[O:15][CH2:14]1.Cl>O>[CH3:12][C@@H:13]1[N:34]2[C:17]3[C:18]([C:30]([C:32]([C:35]([OH:37])=[O:36])=[CH:33]2)=[O:31])=[CH:19][C:20]([F:29])=[C:21]([N:22]2[CH2:23][CH2:24][N:25]([CH3:28])[CH2:26][CH2:27]2)[C:16]=3[O:15][CH2:14]1.[C:1]([O-:10])(=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

참가 물질

6

반응물 3

HCID 313Hydrochloric AcidHCID 149096LevofloxacinHCID 23664772Sodium octanoate

생성물 2

HCID 119389OctanoateHCID 149096Levofloxacin

시약·촉매·용매 1

HCID 962Water용매

실험 절차

One gram of sodium octanoate and one gram of levofloxacin were dissolved in 100 ml water. The pH was slowly adjusted to 6.0 by the addition of 1 M HCl. As the pH decreased, levofloxacin became protonated formed an insoluble HIP with the negatively charged octanoate. The precipitate was gathered by filtration to remove excess levofloxacin, dissolved sodium octanoate/octanoic acid, and salt. The sample was lyophilized overnight.

출처 및 근거

ORD 기록
ord-3c6fcf879372438aa17574c118390070
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08974814B2

연결된 노트

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