Pyridine-2-carbonitrile → Cyclopropyl(pyridin-2-yl)methanamine

반응식

Br[CH:2]1[CH2:4][CH2:3]1.[N:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11]#[N:12]>>[CH:2]1([CH:11]([C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][N:5]=2)[NH2:12])[CH2:4][CH2:3]1

참가 물질

반응물 2

HCID 7522Pyridine-2-carbonitrile

HCID 78037Bromocyclopropane

생성물 1

HCID 3912407Cyclopropyl(pyridin-2-yl)methanamine

실험 절차

The title compound was synthesized according to method G, utilizing Mg powder (240 mg, 10 mmol), bromocyclopropane (1.21 g, 10 mmol), picolinonitrile (520 mg, 5 mmol) and

출처 및 근거

ORD 기록: ord-5873e58c550d4001a7c327f44cb8cb18
출처 데이터셋: uspto-grants-2015_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08980934B2

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