Hydrochloric Acid → HCID 86689368, 화합물

HRID 875366노트

반응식

HRID 875366 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([O:11][CH2:12][CH2:13][O:14][CH2:15][CH2:16][O:17][CH2:18][CH2:19][O:20][C:21]2[CH:26]=[CH:25][C:24](/[CH:27]=[CH:28]/[C:29]3[CH:34]=[CH:33][C:32]([N:35](C(OC(C)(C)C)=O)[CH3:36])=[CH:31][CH:30]=3)=[CH:23][CH:22]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[ClH:44]>C(OCC)C>[ClH:44].[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([O:11][CH2:12][CH2:13][O:14][CH2:15][CH2:16][O:17][CH2:18][CH2:19][O:20][C:21]2[CH:26]=[CH:25][C:24](/[CH:27]=[CH:28]/[C:29]3[CH:34]=[CH:33][C:32]([NH:35][CH3:36])=[CH:31][CH:30]=3)=[CH:23][CH:22]=2)(=[O:9])=[O:10])=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 86689367HCID 86689367, 화합물

생성물 1

HCID 86689368HCID 86689368, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

200 mg 2-[2-(2-{4-[(E)-2-{4-[(tert-butoxycarbonyl)(methyl)amino]phenyl}-vinyl]phenoxy}ethoxy)ethoxy]ethyl 4-methylbenzenesulfonate (2c) were dissolved in a 2M solution of HCl in diethyl ether. The mixture was stirred at room temperature for 72 h. The solvent was removed under reduced pressure. Diethyl ether was added and the precipitate was collected, washed with diethyl ether and dried under reduced pressure. 160 mg 2e were obtained as light yellow solid.

후처리

  1. customThe solvent was removed under reduced pressure
  2. additionDiethyl ether was added
  3. customthe precipitate was collected
  4. washwashed with diethyl ether
  5. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-b9be0a7d2b934ec4b615fdcf08d2ef15
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08981156B2

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