4-(Boc-amino)tetrahydropyran-4-carboxylic acid → tert-Butyl [4-({3-(3,4-dimethylphenyl)-5-[(phenylcarbonyl)amino]piperidin-1-yl}carbonyl)tetrahydro-2H-pyran-4-yl]carbamate

반응식

[C:1]([O:5][C:6]([NH:8][C:9]1([C:15]([OH:17])=O)[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.[CH3:42][C:43]1[CH:44]=[C:45]([CH:50]2[CH2:55][NH:54][CH2:53][CH:52]([NH:56][C:57](=[O:64])[C:58]3[CH:63]=[CH:62][CH:61]=[CH:60][CH:59]=3)[CH2:51]2)[CH:46]=[CH:47][C:48]=1[CH3:49]>CN(C)C1C=CN=CC=1.CN(C=O)C>[CH3:42][C:43]1[CH:44]=[C:45]([CH:50]2[CH2:51][CH:52]([NH:56][C:57]([C:58]3[CH:59]=[CH:60][CH:61]=[CH:62][CH:63]=3)=[O:64])[CH2:53][N:54]([C:15]([C:9]3([NH:8][C:6](=[O:7])[O:5][C:1]([CH3:2])([CH3:3])[CH3:4])[CH2:10][CH2:11][O:12][CH2:13][CH2:14]3)=[O:17])[CH2:55]2)[CH:46]=[CH:47][C:48]=1[CH3:49]