Formamide → HCID 14818212, 화합물

HRID 877230

반응식

HRID 877230 반응식
[F:1][C:2]1[CH:3]=[C:4]2[C:9](=O)[O:8][C:6](=[O:7])[C:5]2=[CH:11][C:12]=1[F:13].C([NH2:16])=O>>[F:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:11][C:12]=1[F:13])[C:6](=[O:7])[NH:16][C:9]2=[O:8]

참가 물질

3

반응물 2

HCID 713FormamideHCID 6397454,5-Difluorophthalic Anhydride

생성물 1

HCID 14818212HCID 14818212, 화합물

실험 절차

At 130° C., 1.0 g (5.4 mmol) of 4,5-difluorophthalic anhydride was stirred in 6 ml of formamide for 2 h. After cooling, the reaction mixture was then added to ice-cold water. The precipitated yellow solid was filtered off with suction, washed thoroughly with cold water and dried under high vacuum. This gave 744 mg of a white solid (74.8% of theory).

후처리

  1. temperatureAfter cooling
  2. additionthe reaction mixture was then added to ice-cold water
  3. filtrationThe precipitated yellow solid was filtered off with suction
  4. washwashed thoroughly with cold water
  5. customdried under high vacuum

출처 및 근거

ORD 기록
ord-202235d35c12483ab53dba07875fb838
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08987256B2

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