Isobutyl chloride → 2-(1-benzyl-1H-indole-6-yl)acetic acid

HRID 878976

반응식

HRID 878976 반응식
C(Cl)C(C)C.[CH2:6]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][C:23]([OH:25])=[O:24])[CH:20]=2)[CH:15]=[CH:14]1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[CH2:6]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][C:23]([OH:25])=[O:24])[CH:20]=2)[CH:15]=[CH:14]1)[CH:7]([CH3:12])[CH3:8].[CH2:6]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[C:19]([CH2:22][C:23]([OH:25])=[O:24])[CH:20]=2)[CH:15]=[CH:14]1)[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

참가 물질

4

반응물 2

HCID 10554Isobutyl chlorideHCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acid

생성물 2

HCID 544889242-(1-benzyl-1H-indole-6-yl)acetic acidHCID 681837802-(1-isobutyl-1H-indole-6-yl)acetic acid

실험 절차

The titled compound (10 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and isobutyl chloride according to the method of the process (7) of Example 4.

출처 및 근거

ORD 기록
ord-9ae79d3c9d694db1a1621891fe93f6a7
출처 데이터셋
uspto-grants-2015_03
특허 번호
US08987473B2

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