Methanol → 1-[2-(4-Amino-3-methoxypiperidin-1-yl)ethyl]-5,7-difluoroquinolin-2-one

반응식

[C:39](#[N:40])[CH3:41].[CH2:1]([N:8]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:32]1)[CH:9]1[CH:10]([O:30][CH3:31])[CH2:11][N:12]([CH2:15][CH2:16][n:17]2[c:18](=[O:29])[cH:19][cH:20][c:21]3[c:22]([F:28])[cH:23][c:24]([F:27])[cH:25][c:26]23)[CH2:13][CH2:14]1)[c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[CH3:42][OH:43].[OH-:44].[OH-:46].[Pd+2:45]>>[NH2:8][CH:9]1[CH:10]([O:30][CH3:31])[CH2:11][N:12]([CH2:15][CH2:16][n:17]2[c:18](=[O:29])[cH:19][cH:20][c:21]3[c:22]([F:28])[cH:23][c:24]([F:27])[cH:25][c:26]23)[CH2:13][CH2:14]1