Acetic Anhydride → HCID 58201210, 화합물

HRID 882988노트

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HRID 882988 반응식
[Cl:1][C:2]1[C:3]([CH3:11])=[N+:4]([O-])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[C:12]([O:15]C(=O)C)(=[O:14])[CH3:13]>>[C:12]([O:15][CH2:11][C:3]1[C:2]([Cl:1])=[C:7]([O:8][CH3:9])[CH:6]=[CH:5][N:4]=1)(=[O:14])[CH3:13]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 13682775HCID 13682775, 화합물

생성물 1

HCID 58201210HCID 58201210, 화합물

실험 절차

The above 3-chloro-4-methoxy-2-methylpyridin-1-oxide (890 mg) was dissolved in acetic anhydride (12 mL), and the resulting solution was then heated under reflux for 30 minutes. After leaving to cool to room temperature, the reaction solution was concentrated under reduced pressure, and the residue was then purified by silica gel chromatography (hexane-ethyl acetate), so as to obtain the title compound (576 mg) as an oily substance.

후처리

  1. temperaturethe resulting solution was then heated
  2. temperatureunder reflux for 30 minutes
  3. customAfter leaving
  4. concentrationthe reaction solution was concentrated under reduced pressure
  5. customthe residue was then purified by silica gel chromatography (hexane-ethyl acetate)

출처 및 근거

ORD 기록
ord-25487b5b32154249bbc9d66a413d549e
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08236813B2

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