Spermine → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

반응식

NCCCNCCCCNCCCN.[C@@H:15]1([O:46]P(O)(O)=O)[C@@H:20]([O:21]P(O)(O)=O)[C@H:19]([O:26]P(O)(O)=O)[C@@H:18]([O:31]P(O)(O)=O)[C@@H:17]([O:36]P(O)(O)=O)[C@H:16]1[O:41]P(O)(O)=O>>[O:21]=[CH:20][C@@H:19]([C@H:18]([C@@H:17]([C@@H:16]([CH2:15][OH:46])[OH:41])[OH:36])[OH:31])[OH:26]

참가 물질

반응물 2

HCID 1103Spermine

HCID 178527091HCID 178527091, 화합물

생성물 1

HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

실험 절차

A composition contemplated by the instant invention was prepared by dissolving human insulin with spermine and phytic acid in double distilled water (“DDW”) containing NaOH. The solution was then lyophilized and suspended with sodium dodecanoate (SD), octanol and geraniol in a mixture of mineral oil, medium chain triglyceride (MCT) oil and castor oil. Components and concentrations are detailed in Table 1.

후처리

customwas prepared
distillationin double distilled water (“DDW”)
additioncontaining NaOH
additionsuspended with sodium dodecanoate (SD), octanol and geraniol in a mixture of mineral oil, medium chain triglyceride (MCT) oil and castor oil
concentrationComponents and concentrations

출처 및 근거

ORD 기록: ord-d34855ce44584ab087d42f08dc818a1c
출처 데이터셋: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08241670B2

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