반응식
C([O:3][C:4](=[O:28])[CH2:5][C:6]1[CH:11]=[C:10]([Cl:12])[CH:9]=[C:8]([O:13][C:14]2[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][C:15]=2[CH2:21][N:22]2[CH2:26][CH2:25][O:24][C:23]2=[O:27])[CH:7]=1)C.[OH-].[Li+]>CO.O>[Br:20][C:17]1[CH:18]=[CH:19][C:14]([O:13][C:8]2[CH:7]=[C:6]([CH2:5][C:4]([OH:28])=[O:3])[CH:11]=[C:10]([Cl:12])[CH:9]=2)=[C:15]([CH2:21][N:22]2[CH2:26][CH2:25][O:24][C:23]2=[O:27])[CH:16]=1참가 물질
5
반응 조건
- 온도
- 60 °C
실험 절차
{3-[4-Bromo-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-5-chloro-phenyl}-acetic acid ethyl ester (0.06 g, 0.13 mmol) in MeOH and H2O was treated with lithium hydroxide, and the reaction was stirred at 60° C. for 30 minutes to give the title compound.
출처 및 근거
- ORD 기록
- ord-109d67210c824d2197eab30e47144060
- 출처 데이터셋
- uspto-grants-2012_08
- 특허 번호
- US08242145B2
연결된 노트
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