Bromomethylcyclopropane → 4-(1-Cyclopropylmethyl-2-methyl-1H-imidazol-4-ylethynyl)-2-methyl-pyridine

반응식

[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.Br[CH2:17][CH:18]1[CH2:20][CH2:19]1>>[CH:18]1([CH2:17][N:13]2[CH:14]=[C:10]([C:9]#[C:8][C:6]3[CH:5]=[CH:4][N:3]=[C:2]([CH3:1])[CH:7]=3)[N:11]=[C:12]2[CH3:15])[CH2:20][CH2:19]1

참가 물질

반응물 2

HCID 81503Bromomethylcyclopropane

HCID 178418884HCID 178418884, 화합물

생성물 1

HCID 114366594-(1-Cyclopropylmethyl-2-methyl-1H-imidazol-4-ylethynyl)-2-methyl-pyridine

실험 절차

The title compound, MS: m/e=252.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and bromomethyl-cyclopropane.

출처 및 근거

ORD 기록: ord-8c01d5a67ec54e1bb487f4e4048478ff
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07091222B2

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