Bromomethylcyclopropane → 2-Chloro-4-(1-cyclopropylmethyl-2-methyl-1H-imidazol-4-ylethynyl)-pyridine

HRID 8870

반응식

HRID 8870 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.Br[CH2:17][CH:18]1[CH2:20][CH2:19]1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([CH2:17][CH:18]3[CH2:20][CH2:19]3)[CH:14]=2)[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 81503BromomethylcyclopropaneHCID 178418879HCID 178418879, 화합물

생성물 1

HCID 112772782-Chloro-4-(1-cyclopropylmethyl-2-methyl-1H-imidazol-4-ylethynyl)-pyridine

실험 절차

The title compound, MS: m/e=272.2 (M+H+), was prepared in accordance with the general method of example 1 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and bromomethyl-cyclopropane.

출처 및 근거

ORD 기록
ord-db53373858a944f39a624b8cd39b18f4
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091222B2

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