Hydrochloric Acid → (2-Oxo-1,2,3,4-tetrahydroquinolin-7-yl)methyl 4-(4-(2-methoxyphenyl)piperazin-1-yl)butanoate hydrochloride

HRID 887075

반응식

HRID 887075 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][C:18]([O:20][CH2:21][C:22]2[CH:31]=[C:30]3[C:25]([CH2:26][CH2:27][C:28](=[O:32])[NH:29]3)=[CH:24][CH:23]=2)=[O:19])[CH2:11][CH2:10]1.[ClH:33]>>[ClH:33].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][CH2:17][C:18]([O:20][CH2:21][C:22]2[CH:31]=[C:30]3[C:25]([CH2:26][CH2:27][C:28](=[O:32])[NH:29]3)=[CH:24][CH:23]=2)=[O:19])[CH2:13][CH2:14]1

참가 물질

3

실험 절차

(2-Oxo-1,2,3,4-tetrahydroquinolin-7-yl)methyl 4-(4-(2-methoxyphenyl)piperazin-1-yl)butanoate hydrochloride (39c) (Scheme 7) was prepared from the compound 38c according to the protocol described for the compound 39a (Example 49). The hydrochloride salt 39c gave satisfactory 1H NMR spectral data. White solid, 0.05 g (31%). MS (ESI): m/z=438.2 (M+H+).

출처 및 근거

ORD 기록
ord-9c24b41c907a4a5386e87c2ab9273e29
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08247420B2

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