Carbon Dioxide → 1-t-Butylimidazole

HRID 888269노트

반응식

HRID 888269 반응식
C=O.[C:3](N)([CH3:6])([CH3:5])[CH3:4].C(=O)([O-])[O-].[NH4+:12].[NH4+:13].[CH:14]([CH:16]=O)=O.[C:18](=O)=O>CO>[C:3]([N:12]1[CH:16]=[CH:14][N:13]=[CH:18]1)([CH3:6])([CH3:5])[CH3:4]

참가 물질

7

반응물 5

HCID 280Carbon DioxideHCID 712FormaldehydeHCID 6385Tert-ButylamineHCID 7860GlyoxalHCID 517111Ammonium Carbonate

생성물 1

HCID 1426651-t-Butylimidazole

시약·촉매·용매 1

HCID 887Methanol용매3회

실험 절차

0.62 mol of paraformaldehyde (18.600 g) is initially charged in 80 ml of methanol. 0.6 mol of tertbutylamine (43.884 g, 63.32 ml) in 80 ml of methanol is cautiously added dropwise thereto with ice cooling. At a temperature of 0° C., 0.3 mol of ammonium carbonate (28.820 g) and 0.6 mol of 40% glyoxal solution (87.040 g, 68.8 mol) in 160 ml of methanol are added. Thereafter, the reaction mixture is warmed to room temperature and stirred overnight, in order that the carbon dioxide formed can escape. Ultimately, the solvent is removed and the product is distilled through a column under high vacuum.

후처리

  1. customformed can
  2. customUltimately, the solvent is removed
  3. distillationthe product is distilled through a column under high vacuum

출처 및 근거

ORD 기록
ord-6d3c87786b924e73982ac11738e3ea10
출처 데이터셋
uspto-grants-2012_08
특허 번호
US08247574B2

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