Lithium Hydroxide → HCID 11260700, 화합물

HRID 890476노트

반응식

HRID 890476 반응식
C([O:3][C:4](=[O:38])[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([O:15][CH2:16][C:17]3[C:18]([CH3:37])=[N:19][C:20]([C:27]4[CH:32]=[CH:31][C:30]([C:33]([F:36])([F:35])[F:34])=[CH:29][CH:28]=4)=[CH:21][C:22]=3[C:23]([F:26])([F:25])[F:24])[CH:13]=2)[CH:8]=[CH:7]1)C.[Li+].[OH-]>>[CH3:37][C:18]1[C:17]([CH2:16][O:15][C:12]2[CH:13]=[C:14]3[C:9]([CH:8]=[CH:7][N:6]3[CH2:5][C:4]([OH:38])=[O:3])=[CH:10][CH:11]=2)=[C:22]([C:23]([F:24])([F:25])[F:26])[CH:21]=[C:20]([C:27]2[CH:28]=[CH:29][C:30]([C:33]([F:35])([F:34])[F:36])=[CH:31][CH:32]=2)[N:19]=1

참가 물질

3

반응물 2

HCID 3939Lithium HydroxideHCID 86597780HCID 86597780, 화합물

생성물 1

HCID 11260700HCID 11260700, 화합물

실험 절차

In analogy to the procedure described in example 5 g], {6-[2-methyl-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl ester was treated with LiOH to obtain the title compound as colorless solid.

출처 및 근거

ORD 기록
ord-3ffcc2be4f0045998d6508f526bdb766
출처 데이터셋
uspto-grants-2006_02
특허 번호
US06995263B2

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