Acetic Acid → N-Acetyl-L-alanine

HRID 890688

반응식

HRID 890688 반응식
[NH2:1][CH:2]([C:4]([OH:6])=[O:5])[CH3:3].[C:7](O)(=[O:9])[CH3:8].C(OC(=O)C)(=O)C>C(OCC)(=O)C>[C:7]([NH:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3])(=[O:9])[CH3:8]

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 602DL-alanineHCID 7918Acetic Anhydride

생성물 1

HCID 88064N-Acetyl-L-alanine

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

반응 조건

온도
100 °C

실험 절차

134 g (1.50 mol) of DL-alanine are introduced into acetic acid and treated dropwise with 230 g (2.25 mol) of acetic anhydride. The mixture is additionally stirred at 100° C. for 2 h to complete the reaction and the solvent is then stripped off in vacuo. The solid obtained is suspended in ethyl acetate and filtered off with suction. For purification, the solid is washed several times with diethyl ether.

후처리

  1. customthe reaction
  2. customThe solid obtained
  3. filtrationfiltered off with suction
  4. customFor purification
  5. washthe solid is washed several times with diethyl ether

출처 및 근거

ORD 기록
ord-7a7506be6c624ae69389ab1b1fb4279d
출처 데이터셋
uspto-grants-2006_02
특허 번호
US06998402B2

연결된 노트

불러오는 중…