Hydrochloric Acid → 4-(2-Methoxyethyl)phenol

HRID 893429

반응식

HRID 893429 반응식
CO[C:3](OC)([C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1)[CH:4]=[O:5].Cl.[H][H].[CH3:18]O>[Pd]>[CH3:18][O:5][CH2:4][CH2:3][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 887MethanolHCID 197888474-Hydroxyphenylglyoxal dimethyl acetalHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 925164-(2-Methoxyethyl)phenol수율 53%

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

The procedure of Example 2 was repeated with a solution of 2.00 g (10.2 mmol) 4-hydroxyphenylglyoxal dimethyl acetal in 10 g methanol containing 0.23 g (6.3) mmol) hydrogen chloride and 0.20 g moist 10% Pd/C catalyst being reacted with hydrogen ga pressurized at 170 psig at 25° C. with stirring of 550 rpm. A 53% yield of 4-(2'-methoxyethyl)phenol was obtained.

후처리

  1. custompressurized at 170 psig at 25° C.

출처 및 근거

ORD 기록
ord-2c93c03c751b426f80ef082d1a0ff4a4
출처 데이터셋
uspto-grants-1992_06
특허 번호
US05124489

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