Methanol → 4-(2-Methoxyethyl)phenol

HRID 893430

반응식

HRID 893430 반응식
CO[C:3](OC)([C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1)[CH:4]=[O:5].[CH3:15]O.[H][H]>[Pd]>[CH3:15][O:5][CH2:4][CH2:3][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1

참가 물질

5

반응물 3

HCID 887MethanolHCID 197888474-Hydroxyphenylglyoxal dimethyl acetalHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 925164-(2-Methoxyethyl)phenol수율 59%

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

The procedure of Example 2 was repeated with a solution of 3.00 g (15.3 mmol) 4-hydroxyphenylglyoxal dimethyl acetal in 10 g methanol containing 0.16 g (4.4 mmol) hydrogen chloride and 0.15 g moist 10% Pd/C catalyst being reacted with hydrogen gas pressurized at 300 psig at 50° C. 300 rpm. A 59% yield of 4-(2'-methoxyethyl)phenol was obtained.

후처리

  1. custompressurized at 300 psig at 50° C

출처 및 근거

ORD 기록
ord-c8d27b60dd4f4624ba1f8e4193a867b2
출처 데이터셋
uspto-grants-1992_06
특허 번호
US05124489

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