Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5-Hexanedione → 2-(2,5-dimethyl-1H-pyrrol-1-yl)-1H-isoindole-1,3(2H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5-Hexanedione | HCID 8035 | — |
| 반응물 | N-Aminophthalimide | HCID 74645 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-(2,5-dimethyl-1H-pyrrol-1-yl)-1H-isoindole-1,3(2H)-dione | HCID 2817169 | 98% |
반응 단계
A mixture of N-amino-phthalimide (50 g) and 2,5-hexadione (35.2 g) in 400 ml acetic acid was refluxed for 48 hours, stripped of solvent, slurried in methylene chloride and filtered. The filtrate was washed with saturated sodium bicarbonate solution, dried and stripped to yield N-(2,5-dimethylpyrrol-1-yl)-phthalimide (98%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04282028 |
| 출처 데이터셋 | uspto-grants-1981_08 |
| ORD ID | ord-dfc76c2b2d994cfcb531a12813a8a835 |
| 출처 메모 | uspto-grants-1981_08 |