Hydrochloric Acid → 2-Ethyl-3-(3-mercapto-2-methylpropanoyl)-4-thiazolidinecarboxylic acid
반응식
C([S:4][CH2:5][CH:6]([CH3:19])[C:7]([N:9]1[CH:13]([C:14]([OH:16])=[O:15])[CH2:12][S:11][CH:10]1[CH2:17][CH3:18])=[O:8])(=O)C.Cl>O.N>[CH2:17]([CH:10]1[N:9]([C:7](=[O:8])[CH:6]([CH3:19])[CH2:5][SH:4])[CH:13]([C:14]([OH:16])=[O:15])[CH2:12][S:11]1)[CH3:18]참가 물질
5
실험 절차
3-(3-Acetylthio-2-methylpropanoyl)-2-ethyl-4-thiazolidinecarboxylic acid (1 g.) is dissolved in a mixture of water (3 ml.) and concentrated ammonia (3 ml.) under a blanket of argon. The mixture is stirred at room temperature for thirty minutes and acidified with concentrated hydrochloric acid. The organic layer is dried and concentrated to dryness in vacuo to yield 2-ethyl-3-(3-mercapto-2-methylpropanoyl)-4-thiazolidinecarboxylic acid.
후처리
- customThe organic layer is dried
- concentrationconcentrated to dryness in vacuo
출처 및 근거
- ORD 기록
- ord-1d78955449c64d8db336bb233f9b684d
- 출처 데이터셋
- uspto-grants-1981_08
- 특허 번호
- US04282235
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