Nitric Acid → 2(3H)-Benzothiazolone, 6-nitro-

HRID 896505

반응식

HRID 896505 반응식
[S:1]1(=O)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[N+:11]([O-])([OH:13])=[O:12].C(OC(=O)C)(=[O:17])C>>[N+:11]([C:7]1[CH:8]=[CH:9][C:4]2[NH:3][C:2](=[O:17])[S:1][C:5]=2[CH:6]=1)([O-:13])=[O:12]

참가 물질

4

반응물 3

HCID 944Nitric AcidHCID 7918Acetic AnhydrideHCID 53400715Benzothiazolinone

생성물 1

HCID 6415712(3H)-Benzothiazolone, 6-nitro-

반응 조건

온도
-10 °C

실험 절차

0.1 mol of benzothiazolinone is dissolved in 100 ml of acetic anhydride and the solution is cooled to −10° C. 10 ml of nitric acid are then added dropwise, and the reaction is stirred for 2 hours. The resulting precipitate is filtered off and washed with water, and then purified by chromatography (eluant CH2Cl2 then AcOEt) to yield the title product, which is recrystallised from ethanol.

후처리

  1. filtrationThe resulting precipitate is filtered off
  2. washwashed with water
  3. custompurified by chromatography (eluant CH2Cl2

출처 및 근거

ORD 기록
ord-1fbddb1298af4da6a2867526236a7614
출처 데이터셋
uspto-grants-2005_07
특허 번호
US06919362B2

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