[2-(2-Chloro-4-nitrophenyl)ethyl]diethylamine → 3-Chloro-4-(2-diethylaminoethyl)phenylamine

HRID 898552노트

반응식

HRID 898552 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[CH2:11][CH2:12][N:13]([CH2:16][CH3:17])[CH2:14][CH3:15].[H][H]>[Ni].C1COCC1>[Cl:1][C:2]1[CH:7]=[C:6]([NH2:8])[CH:5]=[CH:4][C:3]=1[CH2:11][CH2:12][N:13]([CH2:16][CH3:17])[CH2:14][CH3:15]

참가 물질

5

반응물 2

HCID 68816908[2-(2-Chloro-4-nitrophenyl)ethyl]diethylamineHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 596916173-Chloro-4-(2-diethylaminoethyl)phenylamine

시약·촉매·용매 2

HCID 935Nickel촉매HCID 8028Tetrahydrofuran용매

실험 절차

A suspension of 2.00 g (7.790 mmol) [2-(2-chloro-4-nitro-phenyl)-ethyl]-diethyl-amine and 0.80 g Raney nickel in THF was hydrogenated for 2.5 h at RT and 25 psi hydrogen pressure. The catalyst was filtered off and the filtrate evaporated down i. vac.

후처리

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate evaporated down i

출처 및 근거

ORD 기록
ord-53c17b045afb46c680947db18f8e2a89
출처 데이터셋
uspto-grants-2008_04
특허 번호
US07351719B2

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