3-(2-Chloro-4-nitro-phenyl)-prop-2-yn-1-ol → 3-(2-Chloro-4-nitro-phenyl)-propan-1-ol

HRID 898553노트

반응식

HRID 898553 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[C:11]#[C:12][CH2:13][OH:14].[H][H]>[Ni].C1COCC1>[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[CH:4][C:3]=1[CH2:11][CH2:12][CH2:13][OH:14]

참가 물질

5

반응물 2

HCID 230064163-(2-Chloro-4-nitro-phenyl)-prop-2-yn-1-olHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 688779703-(2-Chloro-4-nitro-phenyl)-propan-1-ol

시약·촉매·용매 2

HCID 935Nickel촉매HCID 8028Tetrahydrofuran용매

실험 절차

A suspension of 1.25 g (6.808 mmol) 3-(2-chloro-4-nitro-phenyl)-prop-2-yn-1-ol and 1.00 g Raney nickel in 50 mL THF was hydrogenated for 12 h at RT and 25 psi hydrogen pressure. The catalyst was filtered off and the filtrate was evaporated down i. vac.

후처리

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated down i

출처 및 근거

ORD 기록
ord-09c178bafa9f4658a483d396244039d4
출처 데이터셋
uspto-grants-2008_04
특허 번호
US07351719B2

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