Acetyl chloride → 1-(2-Methoxy-benzylidene)pyrrolidinium chloride

HRID 8999

반응식

HRID 8999 반응식
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:6][O:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=O.C([Cl:19])(=O)C>>[Cl-:19].[CH3:6][O:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH:10]=[N+:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

4

반응물 3

HCID 6367Acetyl chlorideHCID 86582-MethoxybenzaldehydeHCID 31268Pyrrolidine

생성물 1

HCID 179122531-(2-Methoxy-benzylidene)pyrrolidinium chloride

실험 절차

The reaction of 6.9 ml (0.084 mol) pyrrolidine and 4.8 g (0.035 mol) 2-methoxybenzaldehyde in accordance with general synthesis instructions 2 and subsequent reaction with 2.1 ml (0.035 mol) acetyl chloride in accordance with general synthesis instructions 3 gave 6.2 g (corresponding to 78% of the yield calculated by theory) 1-(2-methoxy-benzylidene)-pyrrolidinium chloride.

후처리

  1. customwith general synthesis instructions 3

출처 및 근거

ORD 기록
ord-c64f81c0b04347839e9f8f49788d19e9
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

연결된 노트

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