Hydrazine → Cyclohexanecarbohydrazide

HRID 900138

반응식

HRID 900138 반응식
[CH:1]1([C:7]([O:9]C)=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:11][NH2:12]>CO>[CH:1]1([C:7]([NH:11][NH2:12])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 9321HydrazineHCID 20748Methyl cyclohexanecarboxylate

생성물 1

HCID 240039Cyclohexanecarbohydrazide수율 33.5%

시약·촉매·용매 1

HCID 887Methanol용매

반응 조건

온도
65 °C

실험 절차

To a solution of methyl cyclohexane carboxylate (12 g, 83.9 mmol) in MeOH (50 mL) was added hydrazine (5.3 mL, 1.67 mol). The reaction mixture was heated at 65° C. overnight. The reaction mixture was cooled to room temperature and the resultant solid was collected by filtration and was dried in vacuo to give 4.0 g of cyclohexanecarboxylic acid hydrazide.

후처리

  1. temperatureThe reaction mixture was cooled to room temperature
  2. filtrationthe resultant solid was collected by filtration
  3. customwas dried in vacuo

출처 및 근거

ORD 기록
ord-0f7b1b1ab58e47aa88a8b07dc365b917
출처 데이터셋
uspto-grants-2008_04
특허 번호
US07358242B2

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