Mesitylene → HCID 68964218, 화합물

반응식

C([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([Cl:11])[C:6]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[Cl:18])C=C.[C:19]1(C)[CH:24]=C(C)C=C(C)[CH:20]=1>>[CH2:24]([C:10]1[CH:9]=[CH:8][C:7]([Cl:11])=[C:6]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[Cl:18])[C:5]=1[OH:4])[CH:19]=[CH2:20]

참가 물질

반응물 2

HCID 7947Mesitylene

HCID 69117603HCID 69117603, 화합물

생성물 1

HCID 68964218HCID 68964218, 화합물수율 77%

실험 절차

A solution of 2-allyloxy-2′,6-dichlorobiphenyl (11.6 g, 41.8 mmol) in mesitylene (100 mL) was refluxed for 24 h. The solvent was removed under reduced pressure. Purification by ISCO using a solvent gradient of 0 to 20% ethyl acetate in hexanes provided 9.0 g (77%) of 3-allyl-2′,6-dichlorobiphenyl-2-ol as a light yellow oil.

후처리

customThe solvent was removed under reduced pressure
customPurification by ISCO

출처 및 근거

ORD 기록: ord-bb600922c573405eaeb5a352cda408dd
출처 데이터셋: uspto-grants-2008_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07365095B2

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