5-Benzyloxyindole → 5-Benzyloxy-3-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-1H-indole

HRID 9026

반응식

HRID 9026 반응식
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][CH:13]=[CH:12]2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl-].[CH3:19][O:20][C:21]1[CH:32]=[CH:31][CH:30]=[CH:29][C:22]=1[CH:23]=[N+:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][CH:13]=[C:12]2[CH:23]([C:22]1[CH:29]=[CH:30][CH:31]=[CH:32][C:21]=1[O:20][CH3:19])[N:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 146245-BenzyloxyindoleHCID 179122531-(2-Methoxy-benzylidene)pyrrolidinium chloride

생성물 1

HCID 102951725-Benzyloxy-3-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-1H-indole

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 5-benzyloxy-1H-indole and 1-(2-methoxy-benzylidene)-pyrrolidinium chloride, which had been prepared in accordance with example 24.

후처리

  1. customhad been prepared in accordance with example 24

출처 및 근거

ORD 기록
ord-2cc8ecebb78e4dc5bf8438e46e65d6c4
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

연결된 노트

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