Phenol → 2,2'-[[3-[(7-Chloro-2-methoxypyrido[3,2-b]quinolin-10-yl)amino]propyl]imino]diethanol dihydrochloride

HRID 903148

반응식

HRID 903148 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](Cl)=[C:7]3[N:15]=[C:14]([O:16][CH3:17])[CH:13]=[CH:12][C:8]3=[N:9][C:10]=2[CH:11]=1.[OH:19][CH2:20][CH2:21][N:22]([CH2:27][CH2:28][OH:29])[CH2:23][CH2:24][CH2:25][NH2:26].C1(O)C=CC=CC=1>>[ClH:1].[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6]([NH:26][CH2:25][CH2:24][CH2:23][N:22]([CH2:27][CH2:28][OH:29])[CH2:21][CH2:20][OH:19])=[C:7]3[N:15]=[C:14]([O:16][CH3:17])[CH:13]=[CH:12][C:8]3=[N:9][C:10]=2[CH:11]=1

참가 물질

4

반응물 3

HCID 996PhenolHCID 21088(3-Aminopropyl)diethanolamineHCID 231071-Aza-6,9-dichloro-2-methoxyacridine

생성물 1

HCID 233378162,2'-[[3-[(7-Chloro-2-methoxypyrido[3,2-b]quinolin-10-yl)amino]propyl]imino]diethanol dihydrochloride

실험 절차

A mixture of 2.8 g. of 7,10-dichloro-2-methoxypyrido [3,2-b]quinoline, 1.8 g. of 3-[bis(2-hydroxyethyl)amino]propylamine and 6.5 g. of phenol was treated as in Example 5 to obtain the title compound, m.p. 243°-245° C.

후처리

  1. additionA mixture of 2.8 g

출처 및 근거

ORD 기록
ord-6788092a4d6a49daa3c6958cbbf673e1
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04226869

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