Azide → 1-Amino-3-acetoxy acetone

HRID 903195

반응식

HRID 903195 반응식
[N:1]([CH2:4][C:5]([CH2:7][O:8][C:9](=[O:11])[CH3:10])=[O:6])=[N+]=[N-].[N-]=[N+]=[N-]>C(OC(=O)C)C.[Pd]>[NH2:1][CH2:4][C:5]([CH2:7][O:8][C:9](=[O:11])[CH3:10])=[O:6]

참가 물질

5

반응물 2

HCID 33558AzideHCID 144347801-Azido-3-acetoxyacetone

생성물 1

HCID 221655021-Amino-3-acetoxy acetone

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

1-Azido-3-acetoxyacetone (15.7 g.) is dissolved in ethylacetate (200 ml.). The 10% palladium on carbon catalyst (1.0 g.) is added; the mixture is reduced under hydrogen at atmospheric pressure until the infrared spectrum of an aliquot indicates the absence of the azide. The catalyst is filtered off and the filtrate is evaporated to afford 1-amino-3-acetoxy acetone.

후처리

  1. filtrationThe catalyst is filtered off
  2. customthe filtrate is evaporated

출처 및 근거

ORD 기록
ord-44403b84da5b4bf499d6bc0f5f0501bb
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04226866

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