Methyl Isocyanate → N-Methyl-N'-[2-(3-pyridazinylmethylamino)ethyl]urea

HRID 903245노트

반응식

HRID 903245 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH:8][CH2:9][CH2:10][NH2:11])[N:2]=1.[CH3:12][N:13]=[C:14]=[O:15]>>[CH3:12][NH:13][C:14]([NH:11][CH2:10][CH2:9][NH:8][CH2:7][C:3]1[N:2]=[N:1][CH:6]=[CH:5][CH:4]=1)=[O:15]

참가 물질

3

반응물 2

HCID 12228Methyl IsocyanateHCID 21698444N-(3-pyridazinylmethyl)ethylenediamine

생성물 1

HCID 20557601N-Methyl-N'-[2-(3-pyridazinylmethylamino)ethyl]urea

실험 절차

Reacting N-(3-pyridazinylmethyl)ethylenediamine with methyl isocyanate by the procedure of Example 24, then concentrating and separating the residue by column chromatography gives the title compound.

후처리

  1. concentrationconcentrating
  2. customseparating the residue by column chromatography

출처 및 근거

ORD 기록
ord-ed8a784dfc91406da7d64cf42caed07e
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04226874

반응 노트

불러오는 중…