Acetic Anhydride → (Z,Z)-11,13-Hexadecadienal

HRID 903497

반응식

HRID 903497 반응식
[CH2:1]([OH:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]/[CH:11]=[CH:12]\[CH:13]=[CH:14]/[CH2:15][CH3:16].C(OC(=O)C)(=O)C>N1C=CC=CC=1.C(=O)(O)[O-].[Na+]>[CH:1](=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]/[CH:11]=[CH:12]\[CH:13]=[CH:14]/[CH2:15][CH3:16]

참가 물질

5

반응물 2

HCID 7918Acetic AnhydrideHCID 536556311,13-Hexadecadien-1-ol, (11Z,13Z)-

생성물 1

HCID 6436739(Z,Z)-11,13-Hexadecadienal

시약·촉매·용매 2

HCID 1049Pyridine용매HCID 516892Sodium Bicarbonate용매

실험 절차

(11Z,13Z)-11,13-hexadecadien-1-ol (3.19 mmol) and acetic anhydride (6.38 mmol), in 5 ml of dry pyridine, are stirred under nitrogen at room temperature for 20 hours. The reaction mixture is then poured in sodium bicarbonate solution and extracted with pentane (2X). The organic layer is washed with dilute HCl and with brine, dried over magnesium sulfate and the solvent removed in vacuo. The crude product is purified to yield the final product, (11Z,13Z)-11,13-hexadecadien-1-al.

후처리

  1. extractionextracted with pentane (2X)
  2. washThe organic layer is washed with dilute HCl and with brine
  3. dry with materialdried over magnesium sulfate
  4. customthe solvent removed in vacuo
  5. customThe crude product is purified

출처 및 근거

ORD 기록
ord-904733ac283b49fcabdacd2e6817bb08
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04228093

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