Methyl isothiocyanate → N-methyl-N'-[2-((4-chloro-2-methyl-5-pyrimidyl)methylthio)ethyl]thiourea
반응식
[H-].[Na+].C[N:4]=[C:5]=S.[Cl:7]CC1N=CC=CN=1.C1(=O)[N:19]([CH2:20][CH2:21][CH2:22][SH:23])[C:18](=O)[C:17]2=CC=CC=C12.[CH3:30][NH:31][C:32]([NH:34][CH2:35][CH2:36]CSCC1N=CC=CN=1)=[S:33]>>[CH3:30][NH:31][C:32]([NH:34][CH2:35][CH2:36][S:23][CH2:22][C:21]1[C:5]([Cl:7])=[N:4][C:18]([CH3:17])=[N:19][CH:20]=1)=[S:33]참가 물질
6
반응물 5
생성물 1
실험 절차
In the procedure of Example 1(i) (b) and (ii), using 2-chloromethylpyrimidine and 3-phthalimidopropanethiol as the starting materials, the product is N-methyl-N'-[3-(2-pyrimidylmethylthio)propyl]thiourea.
출처 및 근거
- ORD 기록
- ord-69acbada7fb246f98b947985350b415d
- 출처 데이터셋
- uspto-grants-1980_10
- 특허 번호
- US04230865
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