Ammonium → 3,4-Dimethylpyrrolidine-2,5-dione

HRID 904718

반응식

HRID 904718 반응식
[CH3:1][CH:2]([CH:6]([CH3:10])[C:7](O)=[O:8])[C:3](O)=[O:4].[NH4+:11].Cl>C(OCC)(=O)C>[CH3:1][CH:2]1[CH:6]([CH3:10])[C:7](=[O:8])[NH:11][C:3]1=[O:4]

참가 물질

5

반응물 3

HCID 223AmmoniumHCID 313Hydrochloric AcidHCID 118482,3-Dimethylsuccinic acid

생성물 1

HCID 35508663,4-Dimethylpyrrolidine-2,5-dione

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

반응 조건

온도
60 °C

실험 절차

1 g of 2,3-dimethylsuccinic acid (a mixture of D-, L-, and meso-isomers) was added to 10 ml of 28% aqueous ammonium solution. The mixture was heated and stirred at about 60° C. for 1 hour. After cooling, to the reaction mixture was added aqueous hydrochloric acid solution so as to neutralize, and then the mixture was extrated twice with 10 ml of ethyl acetate. The extract was concentrated to obtain 0.73 g of 2,3-dimethylsuccinimide (a mixture of D-, L, and meso-isomers).

후처리

  1. temperatureThe mixture was heated
  2. temperatureAfter cooling, to the reaction mixture
  3. concentrationThe extract was concentrated

출처 및 근거

ORD 기록
ord-64a8af986959487aa0255059ff310410
출처 데이터셋
uspto-grants-1983_12
특허 번호
US04419443

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