Hydrochloric Acid → HCID 13231126, 화합물

HRID 905030노트

반응식

HRID 905030 반응식
[C:1]([CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[CH2:18][CH2:17][N:16]([NH:19]C(OCC)=O)[CH2:15][CH2:14]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[K+].Cl>C(O)C.O>[C:1]([CH2:9][CH2:10][CH2:11][CH2:12][N:13]1[CH2:18][CH2:17][N:16]([NH2:19])[CH2:15][CH2:14]1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

6

반응물 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 13231125HCID 13231125, 화합물

생성물 1

HCID 13231126HCID 13231126, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

21.4 g of the resulting 4-(4-benzoylbutyl)-1-(ethoxycarbonylamino)piperazine was dissolved in 180 ml of ethanol, and a solution of 36.2 g of potassium hydroxide in 36 ml of water was added. The mixture was heated under reflux for 3 hours. The reaction mixture was cooled, and 136 ml of 4N hydrochloric acid was added to form a 4-(4-benzoylbutyl)-1-aminopiperazine solution.

후처리

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 3 hours
  3. temperatureThe reaction mixture was cooled

출처 및 근거

ORD 기록
ord-0a67049f95364f8fb22ad497ed8cf721
출처 데이터셋
uspto-grants-1983_12
특허 번호
US04421754

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