Benzylamine → Racemic cis benzyl-(1-methanesulfonyl-3-methyl-piperidin-4-yl)-amine

HRID 905938노트

반응식

HRID 905938 반응식
[CH3:1][S:2]([N:5]1[CH2:10][CH2:9][C:8](=O)[CH:7]([CH3:12])[CH2:6]1)(=[O:4])=[O:3].[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([NH:20][C@H:8]1[CH2:9][CH2:10][N:5]([S:2]([CH3:1])(=[O:4])=[O:3])[CH2:6][C@H:7]1[CH3:12])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

3

반응물 2

HCID 7504BenzylamineHCID 67386424Racemic 1-methanesulfonyl-3-methyl-piperidin-4-one

생성물 1

HCID 131729153Racemic cis benzyl-(1-methanesulfonyl-3-methyl-piperidin-4-yl)-amine

실험 절차

Racemic cis benzyl-(1-methanesulfonyl-3-methyl-piperidin-4-yl)-amine was prepared in the same manner from racemic 1-methanesulfonyl-3-methyl-piperidin-4-one. In this instance, benzylamine was used instead of (R)-1-phenylethylamine.

출처 및 근거

ORD 기록
ord-bcf661b984c941d1808683aac2a263b1
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08012974B2

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