Hydrochloric Acid → 1-((3-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)methyl)azetidin-3-ol

반응식

[ClH:28].[F:1][c:2]1[cH:3][c:4]([CH:5]=[O:6])[cH:7][cH:8][c:9]1-[c:10]1[s:11][c:12]2[n:13][c:14]([C:19]3([c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:20][CH2:21]3)[cH:15][cH:16][c:17]2[n:18]1.[OH:29][CH:30]1[CH2:31][NH:32][CH2:33]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][N:32]2[CH2:31][CH:30]([OH:29])[CH2:33]2)[cH:7][cH:8][c:9]1-[c:10]1[s:11][c:12]2[n:13][c:14]([C:19]3([c:22]4[cH:23][cH:24][cH:25][cH:26][cH:27]4)[CH2:20][CH2:21]3)[cH:15][cH:16][c:17]2[n:18]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 15142903-Hydroxyazetidine

HCID 591749073-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)benzaldehyde

생성물 1

HCID 446014431-((3-Fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)methyl)azetidin-3-ol

출처 및 근거

ORD 기록: ord-da6eb85431a34c998b3d1531c479d906
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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