Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4-Bromo-1-(bromomethyl)-2-chlorobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Azobisisobutyronitrile | HCID 6547 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 4-Bromo-2-chlorotoluene | HCID 2735554 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 4-Bromo-1-(bromomethyl)-2-chlorobenzene | HCID 21914486 | 55.3% |
반응 단계
5.0 g of 2-chloro-4-bromotoluene are dissolved in 120 ml of CCl4. 4.3 g of NBS and 1.6 g of AIBN are added. The mixture is heated at reflux for 15 hours, water is added, the two phases are separated and then extraction is carried out with CH2Cl2. Purification is carried out by chromatography on a silica column eluted with petroleum ether. 3.8 g of liquid are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08012991B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-1d17187996294ba3befa45d30c8cc81c |
| 출처 메모 | uspto-grants-2011_09 |