Dimethylamine → [(7-Ethyl-1H-indol-3-yl)-(2-methoxy-phenyl)-methyl]-dimethyl-amine

반응식

[CH2:1]([C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[NH:10][CH:9]=[CH:8]2)[CH3:2].[Cl-].[CH3:13][O:14][C:15]1[CH:24]=[CH:23][CH:22]=[CH:21][C:16]=1[CH:17]=[N+:18]([CH3:20])[CH3:19].COC1C=CC=CC=1C=O.CNC>>[CH2:1]([C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[NH:10][CH:9]=[C:8]2[CH:17]([N:18]([CH3:19])[CH3:20])[C:16]1[CH:21]=[CH:22][CH:23]=[CH:24][C:15]=1[O:14][CH3:13])[CH3:2]

참가 물질

반응물 4

HCID 674Dimethylamine

HCID 86582-Methoxybenzaldehyde

HCID 27247117-Ethylindole

HCID 219853032-Methoxy-benzylidene-dimethyl-ammonium chloride

생성물 1

HCID 21985347[(7-Ethyl-1H-indol-3-yl)-(2-methoxy-phenyl)-methyl]-dimethyl-amine

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 7-ethyl-1H-indole and (2-methoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2-methoxy-benzaldehyde and dimethylamine.