Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric acid magnesium salt (1:1) → HCID 178519079, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 반응물 | 1-benzyl-1H-imidazole-2-carbaldehyde | HCID 139082 | — |
| 반응물 | 4-Amino-1,3-dihydro-2-benzofuran-1-one | HCID 12284649 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | HCID 178519079 | HCID 178519079 | 100.1% |
반응 단계
The mixture of 1-benzyl-1H-imidazole-2-carbaldehyde (430 mg, 1.48 mmol), 4-aminoisobenzofuran-1(3H)-one (221 mg, 1.48 mmol) and magnesium sulfate (4.3 g) in acetonitrile was heated to reflux for 48 hr. Then the mixture was filtrated off and evaporated to remove the solvent. The crude was re-crystallized from isopropanol to obtain the title compound (470 mg, 65%). LC-MS (ESI) m/z: 318 (M+1)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08012976B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-a7b753ab10104293817030635d0a43c4 |
| 출처 메모 | uspto-grants-2011_09 |