4-Aminophenylacetone → 1-(4-Amino-3-chlorophenyl)propan-2-one

HRID 908148노트

반응식

HRID 908148 반응식
[Cl:1]NC(=O)CCC(N)=O.[NH2:10][C:11]1[CH:16]=[CH:15][C:14]([CH2:17][C:18](=[O:20])[CH3:19])=[CH:13][CH:12]=1>C(Cl)(Cl)Cl>[NH2:10][C:11]1[CH:12]=[CH:13][C:14]([CH2:17][C:18](=[O:20])[CH3:19])=[CH:15][C:16]=1[Cl:1]

참가 물질

4

반응물 2

HCID 117883794-AminophenylacetoneHCID 15238416N-chlorosuccinamide

생성물 1

HCID 580124851-(4-Amino-3-chlorophenyl)propan-2-one

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

N-Chlorosuccinamide (1.79 g, 13.4 mmol) is added to a stirred solution of 1-(4-amino-phenyl)-propan-2-one (2.0 g, 13.4 mmol) in chloroform at 0° C. After 1 hour the reaction is complete. The solvent is removed to give the title compound.

후처리

  1. customThe solvent is removed

출처 및 근거

ORD 기록
ord-679a2e7e43a647429ca8cccd7dd4b52e
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08017608B2

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