반응식
[C:1]1([C:7]2N=[CH:9][O:10][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C#[C:19][C:20]([O:22][CH2:23][CH3:24])=[O:21])C=CC=CC=1>C(OCC)(=O)C>[CH2:23]([O:22][C:20]([C:19]1[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:11][O:10][CH:9]=1)=[O:21])[CH3:24]참가 물질
4
반응 조건
- 온도
- 220 °C
실험 절차
Mix 4-Phenyl oxazole (3.33 g, 23.0 mmol) and ethyl phenylpropiolate (4.0 g, 23.0 mmol) in a sealed tube and heat at 220° C. for 20 hours. Perform flash-chromatography on silica gel eluting with 4:1 Hex/ethyl acetate to afford 3.9 g of 4-phenylfuran-3-carboxylic acid ethyl ester as a yellow oil. MS: m/e=217 (MH+).
출처 및 근거
- ORD 기록
- ord-9fd118029536481387b3a1242356d996
- 출처 데이터셋
- uspto-grants-2007_09
- 특허 번호
- US07265246B2
연결된 노트
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