4-Methylmorpholine → HCID 86597248, 화합물

HRID 917415노트

반응식

HRID 917415 반응식
Cl.[CH3:2][O:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][N:12]=1)[C:7]([OH:9])=O.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CN1CCOCC1.[CH3:44][O:45][C:46]1[C:47]2[N:60]=[C:59]([NH2:61])[S:58][C:48]=2[C:49]([N:52]2[CH2:57][CH2:56][O:55][CH2:54][CH2:53]2)=[N:50][CH:51]=1>C1COCC1>[CH3:2][O:3][C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][N:12]=1)[C:7]([NH:61][C:59]1[S:58][C:48]2[C:49]([N:52]3[CH2:57][CH2:56][O:55][CH2:54][CH2:53]3)=[N:50][CH:51]=[C:46]([O:45][CH3:44])[C:47]=2[N:60]=1)=[O:9]

참가 물질

6

반응물 4

HCID 79724-MethylmorpholineHCID 9886157Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 248204212-Methoxyisonicotinic acid hydrochlorideHCID 860385537-Methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-ylamine

생성물 1

HCID 86597248HCID 86597248, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

From 2-methoxy-isonicotinic acid hydrochloride, HATU and N-methylmorpholine in THF, then treatment with 7-methoxy-4-morpholin-4-yl-thiazolo[5,4-c]pyridin-2-ylamine. ES-MS m/e (%): 402 (M+H+, 100).

출처 및 근거

ORD 기록
ord-e36844ae8ef14bd39832824b4361727c
출처 데이터셋
uspto-grants-2007_09
특허 번호
US07273865B2

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