Methanol → 1-Amino-5-methoxyanthracene-9,10-dione

HRID 918541노트

반응식

HRID 918541 반응식
[CH3:1][OH:2].[OH-].[Na+].[NH2:5][C:6]1[C:19]2[C:18](=[O:20])[C:17]3[CH:16]=[CH:15][CH:14]=[C:13](S(O)(=O)=O)[C:12]=3[C:11](=[O:25])[C:10]=2[CH:9]=[CH:8][CH:7]=1>O>[NH2:5][C:6]1[C:19]2[C:18](=[O:20])[C:17]3[C:12](=[C:13]([O:2][CH3:1])[CH:14]=[CH:15][CH:16]=3)[C:11](=[O:25])[C:10]=2[CH:9]=[CH:8][CH:7]=1

참가 물질

5

반응물 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 777241-Aminoanthraquinone-5-sulfonic acid

생성물 1

HCID 138979031-Amino-5-methoxyanthracene-9,10-dione수율 80%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

40 parts by volume of methanol and 10 parts of sodium hydroxide are dissolved at the boil and 13.3 parts of 1-aminoanthraquinone-5-sulphonic acid are introduced into this solution at 80°C, over the course of 30 minutes, with vigorous stirring. The mixture is now stirred for a further 3 hours at 80°-85°C until only traces of starting material are still present according to chromatography. The mixture is now diluted with 50 parts of hot water and the product is filtered off, washed with boiling hot water until neutral and dried at 100°-120°C. 8.9 parts of 1-amino-5-methoxy-anthraquinone (80% of theory) are obtained.

후처리

  1. additionare introduced into this solution at 80°C, over the course of 30 minutes, with vigorous stirring
  2. filtrationthe product is filtered off
  3. washwashed
  4. customdried at 100°-120°C

출처 및 근거

ORD 기록
ord-0844405c41a84152bbc8c1bc3c291af8
출처 데이터셋
uspto-grants-1976_07
특허 번호
US03971812

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