Dimethylformamide → HCID 21521210, 화합물

HRID 918554노트

반응식

[N+:1]([C:4]1[CH:5]=[C:6]([CH:12]=[CH:13][CH:14]=1)[N:7]([CH2:10][CH3:11])[CH2:8][CH3:9])([O-:3])=[O:2].P(Cl)(Cl)(Cl)=O.CN(C)[CH:22]=[O:23]>>[N+:1]([C:4]1[CH:5]=[C:6]([N:7]([CH2:10][CH3:11])[CH2:8][CH3:9])[CH:12]=[CH:13][C:14]=1[CH:22]=[O:23])([O-:3])=[O:2]

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 24813Phosphorus oxychloride

HCID 75186Benzenamine, N,N-diethyl-3-nitro-

생성물 1

HCID 21521210HCID 21521210, 화합물수율 27%

반응 조건

온도: 60 °C

실험 절차

38 parts of m-nitrodiethylaniline is introduced into a mixture of 48 parts of phosphorus oxychloride in 120 parts of dimethylformamide. After having been stirred for six hours at 60°C the mixture is poured into ice-water and the precipitate is suction filtered, washed free from acid and recrystallized from acetone. 12 parts (27% of theory) of 2-nitro-4-diethylaminobenzaldehyde having a melting point of 75° to 77°C is obtained. ##SPC15##

후처리

filtrationfiltered
washwashed free from acid
customrecrystallized from acetone

출처 및 근거

ORD 기록: ord-70013bcabfc5405d9cc4978b6a11a009
출처 데이터셋: uspto-grants-1976_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03971821

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