Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 2-amino-2-ethylbutanoate hydrochloride → Ethyl 2-(5-cyclopropyl-6-((tetrahydro-2H-pyran-4-yl)methoxy)picolinamido)-2-ethylbutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 2-amino-2-ethylbutanoate hydrochloride | HCID 24201639 | — |
| 반응물 | 5-Cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid | HCID 71087254 | — |
| 반응물 | 5-Cyclopropyl-6-(tetrahydro-pyran-4-ylmethoxy)-pyridine-2-carboxylic acid | HCID 71087560 | — |
| 생성물 | Ethyl 2-(5-cyclopropyl-6-((tetrahydro-2H-pyran-4-yl)methoxy)picolinamido)-2-ethylbutanoate | HCID 71087540 | — |
반응 단계
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(tetrahydro-pyran-4-ylmethoxy)-pyridine-2-carboxylic acid (which can e.g. be prepared in a similar manner than 5-cyclopropyl-6-(tetrahydro-furan-2-ylmethoxy)-pyridine-2-carboxylic acid (Example 166 b)) and ethyl 2-amino-2-ethylbutanoate hydrochloride (CAN 1135219-29-2) as starting materials. MS (EI): m/e=419.3 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09290451B2 |
| 출처 데이터셋 | uspto-grants-2016_03 |
| ORD ID | ord-d305d977d23d45bab8e1a51fb9de0c3a |
| 출처 메모 | uspto-grants-2016_03 |